Congratulations to Dr. Angela Starkweather, Professor and Associate Dean for Academic Affairs, and Director of the P20 Center for Accelerating Precision Pain Self-Management who has received a subaward of $68,149 from the University of Maryland at Baltimore (UMB) for a newly funded NINR study Physiological, psychological, and genomic factors that predict the transition from acute to chronic pain in patients with traumatic lower extremity fracture.  Dr. Starkweather will work with Drs. Renn and Dorsey of UMB and Dr. Griffioen of University of Delaware to examine physiological, psychological, clinical, and sociodemographic factors predictive of chronic pain phenotype following lower extremity fracture.  In addition, they will test the hypothesis that differences in gene expression will be associated with the chronic pain phenotype following lower extremity fracture.  Their analyses will examine how changes in gene expression differ between extreme phenotypes at baseline and 52 weeks, and construct a database of altered gene expression profiles as well as novel therapeutic targets and pathways for better pain management.

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